Tixel® is a novel thermal fractional skin rejuvenation system covering the treatment spectrum of ablative CO₂ and non-ablative lasers. In ablative mode deep or shallow Products are created. In non-ablative mode Tixel transfers heat to the upper dermis while sparing the epidermis thus generating permeable channels with effective transdermal transfer to hydrophilic molecules.

Based on Thermo-Mechanical Ablation (TMA) technology, the Tixel impacts the targeted tissue almost identically to fractional CO₂ and erbium lasers, however with low pain, safely and at a fraction of the size and cost of a laser. Analgesic creams are not required. Healing is fast and down time short.

Tixel offers a new dimension in compactness, ergonomic design, and operating comfort to its users who will also benefit from significant cost savings in equipment, maintenance, operating costs and in floor space.

Very different from bulky, complex and expensive aesthetic modalities such as CO₂ and erbium laser devices, Novoxel’s Tixel is a light portable device. The handpiece is small and light weight. Unlike lasers, Tixel has no optics, no high power circuits, no scanners and no water pumps; Tixel does not radiate light and does not present eye-safety hazards. Furthermore, Tixel ablation is smoke and particle free and therefore does not require the use of smoke evacuators or protective dust masks. Tixel achieves the right level of tissue coagulation without any bleeding.


Tixel is powered by TMA (Thermo-Mechanical Ablation), a non-laser fractional treatment technology that can transfer thermal energy to the skin very quickly and safely. The energy is emitted through a matrix of tiny pyramid-shaped pins made of biocompatible materials covering a treatment area of 1cm². The pins are heated to a temperature of 400°C, similar to the temperature generated by a CO₂ laser beam when it interacts with the skin.

During treatment, the pins are introduced at a precisely controlled speed to the surface of the skin, after which the thermal energy stored in the pins is rapidly transferred to the skin upon brief contact lasting only a few milliseconds. The ensuant evaporation of water from the skin occurs instantaneously, resulting in the formation of tiny micropores in the treatment zone. The tiny pyramids hold a limited amount of energy and evaporate the upper layers of the skin in a controlled manner without causing burns or charring in the tissue, a side effect often seen with other energy sources such as laser. Two types of tips with different thermal properties are offered: D (ablative) and S (non-ablative).

Tissue evaporation by the tip upon brief contact with the skin


Unlike the typical micropores seen in fractional CO₂ laser treatments, Tixel micropores are free from necrotic tissue. The narrower zones of epidermal and dermal coagulation with Tixel contribute to rapid healing and treatment safety without sacrificing efficacy.

Laser vs Tixel


Tixel can perform either ablative or non-ablative treatments. The extent of thermal damage generated is closely related to the choice of the tip and to pulse duration. By adjusting treatment parameters, the physician can control the extent of ablation, the thermal effect, downtime and duration of healing.


The permeability of porcine skin treated by Tixel to Verapamil Hydrochloride, a hydrophilic drug molecule, MW 495 Da, is presented below. Tixel is useful for pretreating skin in combination with cosmeceuticals.

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